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Proton Pump Inhibitors and Birth Defects

Proton Pump Inhibitors and Birth Defects

Proton pump inhibitors (PPIs) are a group of drugs characterized by their ability to reduce acid production in the stomach. The stomach contains a pump that produces gastric acid, and PPIs work by binding the pump in order to prevent acid from being pumped into the stomach. Popular PPIs, like Nexium, Prevacid and Prilosec, are typically prescribed to patients suffering from Gastroesophageal Reflux Disease (GERD). PPIs are also used off-label to treat ulcers, Zollinger-Ellison Syndrome, H. Pylori infection of the stomach and laryngitis.

Proton Pump Inhibitors Linked to Birth Defects

Recent research has indicated that PPI-use may increase the likelihood of an infant being born with a birth defect, particularly septal defects of the heart. According to a study published by the University of Pennsylvania in 2010, PPI consumption during the early stages of pregnancy was associated with a doubling in the risk of newborn cardiac birth defects.

PPIs are often prescribed to pregnant women in order to treat heart burn symptoms, something that 25 percent of all pregnant women suffer from. The FDA has classified PPIs as Category B, which means that adequate human studies have not yet shown any tendency for the drug to cause birth defects, so data and conclusions from current research should only be considered preliminary.

Other common side effects related to extended PPI-use include:

  • Leg cramps
  • Abnormal heartbeat
  • Nervousness
  • Rash
  • Diarrhea
  • Weakness
  • Muscle pain
  • Dizziness
  • Abdominal pain
  • Headaches

If you or a loved one used a PPI during pregnancy and gave birth to a child with septal heart defects, or have experienced any of these adverse side effects, you may have cause to pursue a dangerous drug claim. Contact one of our PPI birth defect attorneys to begin exploring your legal options. A member of our team will be able to advise you on the best course of action in pursuing legal remedies for your claim.

Proton Pump Inhibitor Birth Defect Lawsuit

If you or a loved one delivered a child with a birth defect after extended PPI-use, you may be eligible to collect compensation for losses from medical bills, lost wages, pain and suffering, and other damages related to the birth injury.

For more information on the legal rights which may be available to PPI birth defect victims or to schedule a no-obligation consultation with one of our dangerous drug attorneys, call our personal injury lawyers today at 1-800-304-9246.



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